Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initial factor that contributes to hepatic steatosis. Our previous study ind...
Main Authors: | Ke Fang, Fan Wu, Guang Chen, Hui Dong, Jingbin Li, Yan Zhao, Lijun Xu, Xin Zou, Fuer Lu |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | BMC Complementary and Alternative Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12906-019-2671-9 |
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