Autotaxin Implication in Cancer Metastasis and Autoimunne Disorders: Functional Implication of Binding Autotaxin to the Cell Surface

Autotaxin (ATX) is an exoenzyme which, due to its unique lysophospholipase D activity, is responsible for the synthesis of lysophosphatidic acid (LPA). ATX activity is responsible for the concentration of LPA in the blood. ATX expression is increased in various types of cancers, including breast can...

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Bibliographic Details
Main Authors: Olivier Peyruchaud, Lou Saier, Raphaël Leblanc
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/1/105