A Case Report of Massive Acetaminophen Poisoning Treated with a Novel “Triple Therapy”: N-Acetylcysteine, 4-Methylpyrazole, and Hemodialysis

A Case Report of Massive Acetaminophen Poisoning Treated with a Novel “Triple Therapy”: N-Acetylcysteine, 4-Methylpyrazole, and Hemodialysis

Massive acetaminophen (N-acetyl-p-aminophenol; APAP) ingestion is characterized by a rapid onset of mitochondrial dysfunction, including metabolic acidosis, lactemia, and altered mental status without hepatotoxicity which may not respond to the standard doses of N-acetylcysteine (NAC). A 64-year-old...

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Bibliographic Details
Main Authors: Emily A. Kiernan, Julie A. Fritzges, Kathryn A. Henry, Kenneth D. Katz
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Emergency Medicine
Online Access:http://dx.doi.org/10.1155/2019/9301432

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