Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides

Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides

A series of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro antimicrobial, antiviral and cytotoxic activities. Antimicrobial results indicated that compounds (11) and (18) were found to be the most e...

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Bibliographic Details
Main Authors: Mahesh Kumar, Kalavathy Ramasamy, Vasudevan Mani, Rakesh Kumar Mishra, Abu Bakar Abdul Majeed, Erik De Clercq, Balasubramanian Narasimhan
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Arabian Journal of Chemistry
Subjects:
Isatin
QSAR
Antimicrobial
Antiviral
Anticancer/cytotoxic
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212002961

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http://www.sciencedirect.com/science/article/pii/S1878535212002961

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