Proteomic Signatures Reveal Differences in Stress Response, Antioxidant Defense and Proteasomal Activity in Fertile Men with High Seminal ROS Levels

Proteomic Signatures Reveal Differences in Stress Response, Antioxidant Defense and Proteasomal Activity in Fertile Men with High Seminal ROS Levels

Elevated levels of reactive oxygen species (ROS) are a major cause of male infertility. However, some men with high seminal ROS levels are still fertile. The main objective of this study was to understand the molecular mechanism(s) responsible for the preservation of fertility in those men. Semen sa...

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Bibliographic Details
Main Authors: Tânia R. Dias, Luna Samanta, Ashok Agarwal, Peter N. Pushparaj, Manesh Kumar Panner Selvam, Rakesh Sharma
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
seminal plasma
spermatozoa
reactive oxygen species
antioxidants
chemiluminescence
proteomics
bioinformatics
differentially expressed proteins
Western blot
Online Access:http://www.mdpi.com/1422-0067/20/1/203

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