Propagation of human prostate tissue from induced pluripotent stem cells

Propagation of human prostate tissue from induced pluripotent stem cells

Abstract Primary culture of human prostate organoids and patient‐derived xenografts is inefficient and has limited access to clinical tissues. This hampers their use for translational study to identify new treatments. To overcome this, we established a complementary approach where rapidly proliferat...

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Bibliographic Details
Main Authors: Anastasia C. Hepburn, Emma L. Curry, Mohammad Moad, Rebecca E. Steele, Omar E. Franco, Laura Wilson, Parmveer Singh, Adriana Buskin, Susan E. Crawford, Luke Gaughan, Ian G. Mills, Simon W. Hayward, Craig N. Robson, Rakesh Heer
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Stem Cells Translational Medicine
Subjects:
androgen receptor
differentiation
induced pluripotent stem cells
organoids
prostate
prostate cancer
Online Access:https://doi.org/10.1002/sctm.19-0286

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