Essential role of TGF-beta/Smad pathway on statin dependent vascular smooth muscle cell regulation.

Essential role of TGF-beta/Smad pathway on statin dependent vascular smooth muscle cell regulation.

<h4>Background</h4>The 3-hydroxy-3-methylglutaryl CoA reductase inhibitors (also called statins) exert proven beneficial effects on cardiovascular diseases. Recent data suggest a protective role for Transforming Growth Factor-beta (TGF-beta) in atherosclerosis by regulating the balance b...

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Main Authors: Juan Rodríguez-Vita, Eva Sánchez-Galán, Beatriz Santamaría, Elsa Sánchez-López, Raquel Rodrigues-Díez, Luís Miguel Blanco-Colio, Jesús Egido, Alberto Ortiz, Marta Ruiz-Ortega
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19088845/?tool=EBI

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