A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is a disease of attention because of increase in prevalence from 20% to 41%. The clinical and pathological conditions in patients with NAFLD range from steatosis alone to nonalcoholic steatohepatitis (NASH) with or without fibrosis to hepatic cancer. In the U...

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Main Authors:	Wei-Fan Hsu, Lee-Yan Sheen, Hung-Jen Lin, Hen-Hong Chang
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Evidence-Based Complementary and Alternative Medicine
Online Access:	http://dx.doi.org/10.1155/2016/6491420

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spelling	doaj-19f4138449a447eebfa6d8082e623dd82020-11-25T00:00:25ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882016-01-01201610.1155/2016/64914206491420A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver DiseaseWei-Fan Hsu0Lee-Yan Sheen1Hung-Jen Lin2Hen-Hong Chang3Division of Hepato-Gastroenterology, Department of Internal Medicine, China Medical University Hospital, Taichung, TaiwanInstitute of Food Science and Technology, National Taiwan University, Taipei, TaiwanSchool of Post-Baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, TaiwanSchool of Post-Baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, TaiwanNonalcoholic fatty liver disease (NAFLD) is a disease of attention because of increase in prevalence from 20% to 41%. The clinical and pathological conditions in patients with NAFLD range from steatosis alone to nonalcoholic steatohepatitis (NASH) with or without fibrosis to hepatic cancer. In the United States, NAFLD was the second-leading indication for liver transplant between 2004 and 2013. Although imaging studies such as magnetic resonance elastography and the use of diagnostic panels and scoring systems can provide a fairly accurate diagnosis of NAFLD, there are few treatment options for patients with mild to moderate disease other than lifestyle modification. Many of the currently used medical treatments have been shown to cause severe side effects and some have been shown to be associated with increased risk for certain types of cancer. In recent years, a number of traditional Chinese herbal treatments have been examined for their potential uses as treatment for NAFLD. In this review, we provide a general overview of NAFLD and a survey of Western pharmacologic drugs currently used to treat the disease as well as the results of recent studies on the effectiveness of traditional Chinese herbal remedies for managing nonalcoholic fatty liver disease.http://dx.doi.org/10.1155/2016/6491420
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Wei-Fan Hsu Lee-Yan Sheen Hung-Jen Lin Hen-Hong Chang
spellingShingle	Wei-Fan Hsu Lee-Yan Sheen Hung-Jen Lin Hen-Hong Chang A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease Evidence-Based Complementary and Alternative Medicine
author_facet	Wei-Fan Hsu Lee-Yan Sheen Hung-Jen Lin Hen-Hong Chang
author_sort	Wei-Fan Hsu
title	A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease
title_short	A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease
title_full	A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease
title_fullStr	A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease
title_full_unstemmed	A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease
title_sort	review of western and traditional chinese medical approaches to managing nonalcoholic fatty liver disease
publisher	Hindawi Limited
series	Evidence-Based Complementary and Alternative Medicine
issn	1741-427X 1741-4288
publishDate	2016-01-01
description	Nonalcoholic fatty liver disease (NAFLD) is a disease of attention because of increase in prevalence from 20% to 41%. The clinical and pathological conditions in patients with NAFLD range from steatosis alone to nonalcoholic steatohepatitis (NASH) with or without fibrosis to hepatic cancer. In the United States, NAFLD was the second-leading indication for liver transplant between 2004 and 2013. Although imaging studies such as magnetic resonance elastography and the use of diagnostic panels and scoring systems can provide a fairly accurate diagnosis of NAFLD, there are few treatment options for patients with mild to moderate disease other than lifestyle modification. Many of the currently used medical treatments have been shown to cause severe side effects and some have been shown to be associated with increased risk for certain types of cancer. In recent years, a number of traditional Chinese herbal treatments have been examined for their potential uses as treatment for NAFLD. In this review, we provide a general overview of NAFLD and a survey of Western pharmacologic drugs currently used to treat the disease as well as the results of recent studies on the effectiveness of traditional Chinese herbal remedies for managing nonalcoholic fatty liver disease.
url	http://dx.doi.org/10.1155/2016/6491420
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A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease

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