Kazinol Q from Broussonetia kazinoki Enhances Cell Death Induced by Cu(ll) through Increased Reactive Oxygen Species
The ability of the flavan kazinol Q (KQ) to induce DNA breakage in the presence of Cu(II) was examined by agarose gel electrophoresis using supercoiled plasmid DNA. In KQ-mediated DNA breakage reaction, the involvement of reactive oxygen species (ROS), H2O2 and O2 - was established by the inhibition...
Main Authors: | Hsue-Yin Hsu, Bai-Luh Wei, Ying-Chieh Chen |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/16/4/3212/ |
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