Kazinol Q from Broussonetia kazinoki Enhances Cell Death Induced by Cu(ll) through Increased Reactive Oxygen Species

The ability of the flavan kazinol Q (KQ) to induce DNA breakage in the presence of Cu(II) was examined by agarose gel electrophoresis using supercoiled plasmid DNA. In KQ-mediated DNA breakage reaction, the involvement of reactive oxygen species (ROS), H2O2 and O2 - was established by the inhibition...

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Bibliographic Details
Main Authors: Hsue-Yin Hsu, Bai-Luh Wei, Ying-Chieh Chen
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Molecules
Subjects:
ROS
Online Access:http://www.mdpi.com/1420-3049/16/4/3212/

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