Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis.

Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis.

Pairing of homologous chromosomes during early meiosis is essential to prevent the formation of aneuploid gametes. Chromosome pairing includes a step of homology search followed by the stabilization of homolog interactions by the synaptonemal complex (SC). These events coincide with dramatic changes...

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Bibliographic Details
Main Authors: Leticia Labrador, Consuelo Barroso, James Lightfoot, Thomas Müller-Reichert, Stephane Flibotte, Jon Taylor, Donald G Moerman, Anne M Villeneuve, Enrique Martinez-Perez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3649994?pdf=render

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