Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice

Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice

Loss of pericytes, an early hallmark of diabetic retinopathy (DR), results in breakdown of the blood-retinal barrier. Endoplasmic reticulum (ER) stress may be involved in this process. The purpose of this study was to examine the effects of ursodeoxycholic acid (UDCA), a known ameliorator of ER stre...

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Bibliographic Details
Main Authors:	Yoo-Ri Chung, Jeong A. Choi, Jae-Young Koh, Young Hee Yoon
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2017/1763292

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