Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice

Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice

Objective: We have shown that one treatment of fever-like whole body hyperthermia (WBH) on mice bearing human breast tumors results in a tumor growth delay. Our goal was to repeat this study in mice bearing human ovarian or colon tumors. We further evaluated this WBH protocol by performing multiple...

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Main Authors: E. A. Repasky, E. Tims, M. Pritchard, R. Burd
Format: Article
Language:English
Published: Hindawi Limited 1999-01-01
Series:Infectious Diseases in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/S1064744999000162
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spelling doaj-19cf593df8ff4d45b94fbdb6a7fcfb2f2020-11-24T23:49:17ZengHindawi LimitedInfectious Diseases in Obstetrics and Gynecology1064-74491098-09971999-01-0171-2919710.1155/S1064744999000162Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient MiceE. A. Repasky0E. Tims1M. Pritchard2R. Burd3Department of Immunology, Roswell Park Cancer Institute, Buffalo 14263, NY, USADepartment of Immunology, Roswell Park Cancer Institute, Buffalo 14263, NY, USADepartment of Immunology, Roswell Park Cancer Institute, Buffalo 14263, NY, USADivision of Radiation Oncology, Thomas Jefferson University Hospital, Philadelpaia, PA, USAObjective: We have shown that one treatment of fever-like whole body hyperthermia (WBH) on mice bearing human breast tumors results in a tumor growth delay. Our goal was to repeat this study in mice bearing human ovarian or colon tumors. We further evaluated this WBH protocol by performing multiple and interrupted WBH treatments.http://dx.doi.org/10.1155/S1064744999000162
collection DOAJ
language English
format Article
sources DOAJ
author E. A. Repasky
E. Tims
M. Pritchard
R. Burd
spellingShingle E. A. Repasky
E. Tims
M. Pritchard
R. Burd
Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice
Infectious Diseases in Obstetrics and Gynecology
author_facet E. A. Repasky
E. Tims
M. Pritchard
R. Burd
author_sort E. A. Repasky
title Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice
title_short Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice
title_full Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice
title_fullStr Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice
title_full_unstemmed Characterization of Mild Whole-Body Hyperthermia Protocols Using Human Breast, Ovarian, and Colon Tumors Grown in Severe Combined Immunodeficient Mice
title_sort characterization of mild whole-body hyperthermia protocols using human breast, ovarian, and colon tumors grown in severe combined immunodeficient mice
publisher Hindawi Limited
series Infectious Diseases in Obstetrics and Gynecology
issn 1064-7449
1098-0997
publishDate 1999-01-01
description Objective: We have shown that one treatment of fever-like whole body hyperthermia (WBH) on mice bearing human breast tumors results in a tumor growth delay. Our goal was to repeat this study in mice bearing human ovarian or colon tumors. We further evaluated this WBH protocol by performing multiple and interrupted WBH treatments.
url http://dx.doi.org/10.1155/S1064744999000162
work_keys_str_mv AT earepasky characterizationofmildwholebodyhyperthermiaprotocolsusinghumanbreastovarianandcolontumorsgrowninseverecombinedimmunodeficientmice
AT etims characterizationofmildwholebodyhyperthermiaprotocolsusinghumanbreastovarianandcolontumorsgrowninseverecombinedimmunodeficientmice
AT mpritchard characterizationofmildwholebodyhyperthermiaprotocolsusinghumanbreastovarianandcolontumorsgrowninseverecombinedimmunodeficientmice
AT rburd characterizationofmildwholebodyhyperthermiaprotocolsusinghumanbreastovarianandcolontumorsgrowninseverecombinedimmunodeficientmice
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