Herbal Remedies with Anthelmintic Action. Myth or Reality

• Main Authors: N. B. Emelyanova, O. P. Kurnosova, M. V. Arisov
• Format: Article
• Language: Russian
• Published: Federal Scientific Centre VIEV 2019-10-01
• Series: Российский паразитологический журнал
• Subjects: phytopreparation; anthelmintic effectiveness
• Online Access: https://vniigis.elpub.ru/jour/article/view/517

The purpose of the research is to study the anthelmintic action of an american drug intended for the treatment and prevention of helminthosis.Materials and methods. A test of the effectiveness of an antiparasitic drug (USA), which includes: extracts of Jerusalem oak, citron seed, pumpkin seeds, male fern, thyme, wheatgrass, pomegranate bark, quartz mineral, table salt, etc. According to the instructions for use, the drug (series 61571-574-15) tested at a dose of 200 mg/kg three times a day for 7 days for the purpose of prevention and for 14 days for treatment. The phytopreparation is intended for the treatment of helminthosis in cats, dogs, rodents and birds. Anthelmintic has no contraindications and side effects, as well as age restrictions. In the experiment, 20 male rats weighing 200–220 g at the age of 3 months were used, spontaneously infected with Syphacia obvelata and Aspiculuris tetraptera (mixed infection). The diagnosis was made on the basis of a study of rat feces samples for the presence of nematode eggs according to the Darling method using a solution of zinc sulfate with a density of 1.32. The number of eggs was counted in 1 g of feces by the conventional method. Animals were divided into equivalent experimental and control groups of 10 animals each. The number of nematode eggs in 1 g of feces amounted to 56.32 specimens for the experimental group. eggs of S. obvelata, 44.44 eggs of A. tetraptera and for the control – 50.60 and 48.52 respectively.Results and discussion. The results obtained indicate the absence of the anthelmintic effect of the american drug against S. obvelata and A. tetraptera in the recommended dose for 21 days. In addition, the animals were not only not released from the nematodes, but also reinfected, which allows us to conclude that there is no preventive effect.