Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy

Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy

Abstract Background Cardiovascular exercise (CVE) has been shown to be protective against cognitive decline in aging and the risk for dementias, including Alzheimer’s Disease (AD). CVE has also been shown to have several beneficial effects on brain pathology and behavioral impairments in mouse model...

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Bibliographic Details
Main Authors: Lisa S. Robison, Dominique L. Popescu, Maria E. Anderson, Nikita Francis, Joshua Hatfield, Joseph K. Sullivan, Steven I. Beigelman, Feng Xu, Brenda J. Anderson, William E. Van Nostrand, John K. Robinson
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Neuroinflammation
Subjects:
Cerebral amyloid angiopathy
Alzheimer’s disease
Exercise
Cardiovascular
Aerobic
Fitness
Online Access:http://link.springer.com/article/10.1186/s12974-019-1534-0

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