Checkpoint Inhibitors as High-Grade Gliomas Treatment: State of the Art and Future Perspectives

Checkpoint Inhibitors as High-Grade Gliomas Treatment: State of the Art and Future Perspectives

<b> </b>Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. Despite significant efforts, no therapies have demonstrated valuable survival benefit beyond the current standard of care. Immune checkpoint inhibitors (ICI) have revolutionized the treatment la...

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Bibliographic Details
Main Authors: Pasquale Persico, Elena Lorenzi, Angelo Dipasquale, Federico Pessina, Pierina Navarria, Letterio S. Politi, Armando Santoro, Matteo Simonelli
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
checkpoint inhibitors
immunotherapy
glioma
glioblastoma
PD-1
PD-L1
Online Access:https://www.mdpi.com/2077-0383/10/7/1367

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