IFN-γ Regulates the Expression of MICA in Human Corneal Epithelium Through miRNA4448 and NFκB

IFN-γ Regulates the Expression of MICA in Human Corneal Epithelium Through miRNA4448 and NFκB

PurposeMajor histocompatibility complex class I-related chain A (MICA), a non-classical major histocompatibility complex molecule, can stimulate or co-stimulate CD8+ T cells or natural killer (nk) cells, thus affecting cornea allograft survival. This study investigated IFN-γ regulation of MICA expre...

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Bibliographic Details
Main Authors: Dan Wu, Jing Zhang, Tingting Qian, Yiqin Dai, Alireza Mashaghi, Jianjiang Xu, Jiaxu Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
IFN-γ
MICA
miRNA4448
NFκB
human corneal epithelium
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01530/full

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