Design, Synthesis, Anticancer Evaluation and Molecular Modeling of Novel Estrogen Derivatives

Design, Synthesis, Anticancer Evaluation and Molecular Modeling of Novel Estrogen Derivatives

A series of estrone derivatives <b>3</b>–<b>8</b> was designed and synthesized using estrone arylmethylenes <b>2a</b>,<b>b</b> as starting materials and their structures were confirmed by different spectral data and elemental analyses. All the newly sy...

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Bibliographic Details
Main Authors: Abd El-Galil E. Amr, Elsayed A. Elsayed, Mohamed A. Al-Omar, Hanan O. Badr Eldin, Eman S. Nossier, Mohamed M. Abdallah
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
estrogen derivatives
design
anticancer evaluation
molecular modeling studies
Online Access:https://www.mdpi.com/1420-3049/24/3/416

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