Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery

Our aim was to provide an in vivo assessment of human muscle twitch characteristics during and following an exhaustive dynamic exercise to explore temporal alterations of the rate of force development (RFD) and relaxation (RFR). Eleven healthy participants (mean age ± SD: 24 ± 3 years) completed a d...

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Main Authors: Fabrice Rannou, Lars Nybo, Janni Enghave Andersen, Nikolai B. Nordsborg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.660099/full
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spelling doaj-1975c582eb22481bbed845ee9a5179442021-07-02T05:11:56ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2021-07-011210.3389/fphys.2021.660099660099Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and RecoveryFabrice Rannou0Fabrice Rannou1Lars Nybo2Janni Enghave Andersen3Nikolai B. Nordsborg4Department of Sport Medicine and Functional Explorations-ASMS, CRNH, CHU Clermont-Ferrand, Clermont-Ferrand, FranceDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, DenmarkDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, DenmarkDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, DenmarkDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, DenmarkOur aim was to provide an in vivo assessment of human muscle twitch characteristics during and following an exhaustive dynamic exercise to explore temporal alterations of the rate of force development (RFD) and relaxation (RFR). Eleven healthy participants (mean age ± SD: 24 ± 3 years) completed a dynamic knee-extensor exercise in randomized order at three different intensities, eliciting exhaustion after ∼9 min (56 ± 10 W), ∼6 min (60 ± 10 W), and ∼4 min (63 ± 10 W), in addition to a low-intensity (28 ± 5 W) bout. In a novel setup, an electrical doublet stimulation of m. vastus lateralis was applied during exercise (every 30 s) and recovery for frequent evaluation of key contractile properties (maximal force, RFD, RFR, and electromechanical delay) in addition to M-wave characteristics. RFD and RFR remained stable throughout the low-intensity trial but declined in all exhaustive trials to reach a similar level of ∼40% of pre-exercise values at task failure but with the exponential decay augmented by intensity. Following exhaustion, there was a fast initial recovery of RFD and RFR to ∼80% of pre-exercise values within 1 min, followed by a longer suppression at this level. The M-wave characteristics remained unchanged during all trials. In conclusion, this is the first study to quantify the intensity-dependent alterations of RFD and RFR during and after exhaustive dynamic exercise in humans. A hypothesized reduction and fast reversion of RFD was confirmed, and a surprising compromised RFR is reported. The present unique experimental approach allows for novel insight to exercise-induced alterations in human muscle contractile properties which is relevant in health and disease.https://www.frontiersin.org/articles/10.3389/fphys.2021.660099/fulldynamic exerciseintramuscular fatigueelectromechanical delayrates of force development and relaxationrecovery
collection DOAJ
language English
format Article
sources DOAJ
author Fabrice Rannou
Fabrice Rannou
Lars Nybo
Janni Enghave Andersen
Nikolai B. Nordsborg
spellingShingle Fabrice Rannou
Fabrice Rannou
Lars Nybo
Janni Enghave Andersen
Nikolai B. Nordsborg
Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery
Frontiers in Physiology
dynamic exercise
intramuscular fatigue
electromechanical delay
rates of force development and relaxation
recovery
author_facet Fabrice Rannou
Fabrice Rannou
Lars Nybo
Janni Enghave Andersen
Nikolai B. Nordsborg
author_sort Fabrice Rannou
title Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery
title_short Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery
title_full Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery
title_fullStr Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery
title_full_unstemmed Muscle Contractile Characteristics During Exhaustive Dynamic Exercise and Recovery
title_sort muscle contractile characteristics during exhaustive dynamic exercise and recovery
publisher Frontiers Media S.A.
series Frontiers in Physiology
issn 1664-042X
publishDate 2021-07-01
description Our aim was to provide an in vivo assessment of human muscle twitch characteristics during and following an exhaustive dynamic exercise to explore temporal alterations of the rate of force development (RFD) and relaxation (RFR). Eleven healthy participants (mean age ± SD: 24 ± 3 years) completed a dynamic knee-extensor exercise in randomized order at three different intensities, eliciting exhaustion after ∼9 min (56 ± 10 W), ∼6 min (60 ± 10 W), and ∼4 min (63 ± 10 W), in addition to a low-intensity (28 ± 5 W) bout. In a novel setup, an electrical doublet stimulation of m. vastus lateralis was applied during exercise (every 30 s) and recovery for frequent evaluation of key contractile properties (maximal force, RFD, RFR, and electromechanical delay) in addition to M-wave characteristics. RFD and RFR remained stable throughout the low-intensity trial but declined in all exhaustive trials to reach a similar level of ∼40% of pre-exercise values at task failure but with the exponential decay augmented by intensity. Following exhaustion, there was a fast initial recovery of RFD and RFR to ∼80% of pre-exercise values within 1 min, followed by a longer suppression at this level. The M-wave characteristics remained unchanged during all trials. In conclusion, this is the first study to quantify the intensity-dependent alterations of RFD and RFR during and after exhaustive dynamic exercise in humans. A hypothesized reduction and fast reversion of RFD was confirmed, and a surprising compromised RFR is reported. The present unique experimental approach allows for novel insight to exercise-induced alterations in human muscle contractile properties which is relevant in health and disease.
topic dynamic exercise
intramuscular fatigue
electromechanical delay
rates of force development and relaxation
recovery
url https://www.frontiersin.org/articles/10.3389/fphys.2021.660099/full
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