Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia

Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia

HDL-associated paraoxonase type 1 (PON1) can protect LDL and HDL against oxidative modification in vitro and therefore may protect against cardiovascular disease. We investigated the effects of PON1 levels, activity, and genetic variation on high density lipoprotein-cholesterol (HDL-C) levels, circu...

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Bibliographic Details
Main Authors: Thomas M. van Himbergen, Mark Roest, Jacqueline de Graaf, Eugène H.J.M. Jansen, Hiroaki Hattori, John J.P. Kastelein, Hieronymus A.M. Voorbij, Anton F.H. Stalenhoef, Lambertus J.H. van Tits
Format: Article
Language:English
Published: Elsevier 2005-03-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
antioxidants
polymorphisms
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340281

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