A method for rapid high-throughput biophysical analysis of proteins

Abstract Quantitative determination of protein thermodynamic stability is fundamental to many research areas, both basic and applied. Although chemical-induced denaturation is the gold-standard method, it has been replaced in many settings by semi-quantitative approaches such as thermal stability me...

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Bibliographic Details
Main Authors: Albert Perez-Riba, Laura S. Itzhaki
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08664-w