Use of Vacuum Therapy in the Treatment of Wounds in Patients with Diabetic Foot Syndrome

• Main Authors: P.O. Herasymchuk, I.M. Deikalo, V.H. Vlasenko, D.B. Fira, A.V. Pavlyshyn
• Format: Article
• Language: English
• Published: Publishing House Zaslavsky 2016-03-01
• Series: Mìžnarodnij Endokrinologìčnij Žurnal
• Subjects: vacuum therapy; laser Doppler fluorometry; microhemodynamics; microbial contamination of the wound.
• Online Access: http://iej.zaslavsky.com.ua/article/view/70953
• ISSN: 2224-0721; 2307-1427

Introduction. Acute and chronic wound defects of the lower extremities occurs in 15–25 % of patients with diabetes mellitus, serving as the direct cause of frequent amputations of lower extremities in 12 % of patients. One of the current and promising directions of wound healing is vacuum therapy. Objective. To study the effect of vacuum therapy on the course of acute and chronic wound process in patients with diabetic foot syndrome, depending on the pathogenic form of the injury, and on the basis of the findings to improve the outcomes of surgical treatment of the above-mentioned pathology. Materials and methods. The study involved 239 patients with complicated forms of diabetic foot syndrome. Monitoring of the wound progress is complemented by clinical, cytological, microbiological and morphological criteria. In the treatment of patients, we have used vacuum therapy device by Agat-Dnepr company. Vacuum therapy of wounds was carried out in the modes of negative pressure within 80–125 mmHg. Results. On the 2nd — 3rd day of vacuum treatment, there was a significant decrease of local manifestations of acute inflammation. At the same time, we have noted a significantly reduction in the amount of wound defects. There were positive changes from the side of wound microbial contamination defects. Application of continuous vacuum therapy in the treatment of wound defects greatly improved the performance of local microcirculation. Conclusions. Use of vacuum therapy in the combination treatment of acute and chronic wounds in patients with diabetic foot syndrome has a local and systemic action that enables to stabilize the course of wound process, to stimulate regenerative processes, to eliminate manifestations of endogenous intoxication and violations of immunological reactivity.