Early Aberrant Angiogenesis Due to Elastic Fiber Fragmentation in Aortic Valve Disease

Early Aberrant Angiogenesis Due to Elastic Fiber Fragmentation in Aortic Valve Disease

Elastic fiber fragmentation (EFF) is a hallmark of aortic valve disease (AVD), and neovascularization has been identified as a late finding related to inflammation. We sought to characterize the relationship between early EFF and aberrant angiogenesis. To examine disease progression, regional anatom...

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Bibliographic Details
Main Authors: Robert B. Hinton, Amy L. Juraszek, Amy M. Opoka, Benjamin J. Landis, J. Michael Smith, Robert P. Mecham, Kevin E. Bove
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
heart valves
aortic root
elastic fiber
angiogenesis
pediatrics
Online Access:https://www.mdpi.com/2308-3425/8/7/75

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https://www.mdpi.com/2308-3425/8/7/75

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