Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes

Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes

The mechanisms underlying the success or failure of fecal microbiota transplantation (FMT) are unclear. Here, Wang et al. use a mouse model of FMT to show that fluorescent D-amino acids can be used to track the transplanted microbiota in the recipient animals.

Bibliographic Details
Main Authors: Wei Wang, Liyuan Lin, Yahui Du, Yanling Song, Xiaoman Peng, Xing Chen, Chaoyong James Yang
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09267-x
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spelling doaj-1946143a64174cbca9e4a7bdee514c222021-05-11T11:59:47ZengNature Publishing GroupNature Communications2041-17232019-03-011011710.1038/s41467-019-09267-xAssessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probesWei Wang0Liyuan Lin1Yahui Du2Yanling Song3Xiaoman Peng4Xing Chen5Chaoyong James Yang6Institute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of MedicineInstitute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of MedicineCollaborative Innovation Center of Chemistry for Energy Materials, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen UniversityInstitute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of MedicineInstitute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of MedicineCollege of Chemistry and Molecular Engineering, Peking-Tsinghua Center for Life Sciences, Synthetic and Functional Biomolecules Center, and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking UniversityInstitute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of MedicineThe mechanisms underlying the success or failure of fecal microbiota transplantation (FMT) are unclear. Here, Wang et al. use a mouse model of FMT to show that fluorescent D-amino acids can be used to track the transplanted microbiota in the recipient animals.https://doi.org/10.1038/s41467-019-09267-x
collection DOAJ
language English
format Article
sources DOAJ
author Wei Wang
Liyuan Lin
Yahui Du
Yanling Song
Xiaoman Peng
Xing Chen
Chaoyong James Yang
spellingShingle Wei Wang
Liyuan Lin
Yahui Du
Yanling Song
Xiaoman Peng
Xing Chen
Chaoyong James Yang
Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes
Nature Communications
author_facet Wei Wang
Liyuan Lin
Yahui Du
Yanling Song
Xiaoman Peng
Xing Chen
Chaoyong James Yang
author_sort Wei Wang
title Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes
title_short Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes
title_full Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes
title_fullStr Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes
title_full_unstemmed Assessing the viability of transplanted gut microbiota by sequential tagging with D-amino acid-based metabolic probes
title_sort assessing the viability of transplanted gut microbiota by sequential tagging with d-amino acid-based metabolic probes
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-03-01
description The mechanisms underlying the success or failure of fecal microbiota transplantation (FMT) are unclear. Here, Wang et al. use a mouse model of FMT to show that fluorescent D-amino acids can be used to track the transplanted microbiota in the recipient animals.
url https://doi.org/10.1038/s41467-019-09267-x
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AT yahuidu assessingtheviabilityoftransplantedgutmicrobiotabysequentialtaggingwithdaminoacidbasedmetabolicprobes
AT yanlingsong assessingtheviabilityoftransplantedgutmicrobiotabysequentialtaggingwithdaminoacidbasedmetabolicprobes
AT xiaomanpeng assessingtheviabilityoftransplantedgutmicrobiotabysequentialtaggingwithdaminoacidbasedmetabolicprobes
AT xingchen assessingtheviabilityoftransplantedgutmicrobiotabysequentialtaggingwithdaminoacidbasedmetabolicprobes
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