Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
Mutation of the nuclear envelope protein, barrier-to-autointegration factor 1 (Banf1), has previously been associated with the development of ageing associated diseases in a human progeria syndrome. Here, the authors reveal the functional link between Banf1-regulated, PARP1-directed repair of oxidat...
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Bibliographic Details
Main Authors: |
Emma Bolderson,
Joshua T. Burgess,
Jun Li,
Neha S. Gandhi,
Didier Boucher,
Laura V. Croft,
Samuel Beard,
Jennifer J. Plowman,
Amila Suraweera,
Mark N. Adams,
Ali Naqi,
Shu-Dong Zhang,
David A. Sinclair,
Kenneth J. O’Byrne,
Derek J. Richard |
Format: | Article
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Language: | English |
Published: |
Nature Publishing Group
2019-12-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-019-13167-5
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