Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease

Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease

Alpha-synuclein is a presynaptic protein expressed throughout the central nervous system, and it is the main component of Lewy bodies, one of the histopathological features of Parkinson’s disease (PD) which is a progressive and irreversible neurodegenerative disorder. The conformational flexibility...

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Bibliographic Details
Main Authors: Scarlet eGallegos, Carla ePacheco, Christian ePeters, Carlos M Opazo, Luis Gerardo Aguayo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson Disease
neurodegeneration
Toxicity
transmission
alpha synuclein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00059/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00059/full

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