Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension

Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging...

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Main Authors:	Shenglin Zhang, Xin Gao, Dongxia Wang, Yinong Jiang, Yan Liu
Format:	Article
Language:	English
Published:	Elsevier 2019-08-01
Series:	International Journal of Cardiology. Hypertension
Subjects:	PAC Atrial function Hypertension
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590086219300151

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spelling	doaj-19317826c50349ac8ab6e0c1c414af7b2021-03-18T04:42:01ZengElsevierInternational Journal of Cardiology. Hypertension2590-08622019-08-012100015Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertensionShenglin Zhang0Xin Gao1Dongxia Wang2Yinong Jiang3Yan Liu4Department of General Surgery, The 1st Affiliated Hospital of Dalian Medical University, Zhongshan Road No. 222, Xigang District, Dalian, Liaoning, ChinaDepartment of Cardiology, The 1st Affiliated Hospital of Dalian Medical University, Lianhe Road, No. 193, Shahekou District, Dalian, Liaoning, ChinaDepartment of Cardiology, The 1st Affiliated Hospital of Dalian Medical University, Lianhe Road, No. 193, Shahekou District, Dalian, Liaoning, ChinaDepartment of Cardiology, The 1st Affiliated Hospital of Dalian Medical University, Lianhe Road, No. 193, Shahekou District, Dalian, Liaoning, ChinaDepartment of Cardiology, The 1st Affiliated Hospital of Dalian Medical University, Lianhe Road, No. 193, Shahekou District, Dalian, Liaoning, China; Corresponding author.Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LAS-E and LASR-E) were lower in group II compared with group I (P < 0.05). Multivariate regression analysis showed that LAS-E was independently related to PAC (β = −0.581, P < 0.001). In conclusion, PAC is associated with LA conduit function in hypertension.http://www.sciencedirect.com/science/article/pii/S2590086219300151PACAtrial functionHypertension
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Shenglin Zhang Xin Gao Dongxia Wang Yinong Jiang Yan Liu
spellingShingle	Shenglin Zhang Xin Gao Dongxia Wang Yinong Jiang Yan Liu Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension International Journal of Cardiology. Hypertension PAC Atrial function Hypertension
author_facet	Shenglin Zhang Xin Gao Dongxia Wang Yinong Jiang Yan Liu
author_sort	Shenglin Zhang
title	Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_short	Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_full	Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_fullStr	Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_full_unstemmed	Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_sort	association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
publisher	Elsevier
series	International Journal of Cardiology. Hypertension
issn	2590-0862
publishDate	2019-08-01
description	Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LAS-E and LASR-E) were lower in group II compared with group I (P < 0.05). Multivariate regression analysis showed that LAS-E was independently related to PAC (β = −0.581, P < 0.001). In conclusion, PAC is associated with LA conduit function in hypertension.
topic	PAC Atrial function Hypertension
url	http://www.sciencedirect.com/science/article/pii/S2590086219300151
work_keys_str_mv	AT shenglinzhang associationbetweenelevatedplasmaaldosteroneconcentrationandleftatrialconduitfunctioninhypertension AT xingao associationbetweenelevatedplasmaaldosteroneconcentrationandleftatrialconduitfunctioninhypertension AT dongxiawang associationbetweenelevatedplasmaaldosteroneconcentrationandleftatrialconduitfunctioninhypertension AT yinongjiang associationbetweenelevatedplasmaaldosteroneconcentrationandleftatrialconduitfunctioninhypertension AT yanliu associationbetweenelevatedplasmaaldosteroneconcentrationandleftatrialconduitfunctioninhypertension
_version_	1724216760429707264

Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension

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