PPAR Gamma and Angiogenesis: Endothelial Cells Perspective
We summarize the current knowledge concerning PPARγ function in angiogenesis. We discuss the mechanisms of action for PPARγ and its role in vasculature development and homeostasis, focusing on endothelial cells, endothelial progenitor cells, and bone marrow-derived proangiogenic cells.
Main Authors: | Jerzy Kotlinowski, Alicja Jozkowicz |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
|
Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2016/8492353 |
Similar Items
-
Regulation of endothelial cell metabolism by agonist-activated PPAR? : implications for angiogenesis-related activity
by: Faulkner, Ashton
Published: (2017) -
PPARs and Angiogenesis—Implications in Pathology
by: Nicole Wagner, et al.
Published: (2020-08-01) -
PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs
by: Serena Vella, et al.
Published: (2016-01-01) -
GW9662, an antagonist of PPAR-gamma, inhibits breast tumour cell growth and promotes the anticancer effects of the PPAR-gamma agonist Rosiglitazone, independently of PPAR-gamma activation.
by: Gill, Jason H., et al.
Published: (2009) -
Fibroblast growth factor 21 enhances angiogenesis and wound healing of human brain microvascular endothelial cells by activating PPARγ
by: Wenting Huang, et al.
Published: (2019-06-01)