Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis

Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis

<p>Abstract</p> <p>Background</p> <p>Granulocyte colony stimulating factor (GCSF) is protective in animal models of various neurodegenerative diseases. We investigated whether pegfilgrastim, GCSF with sustained action, is protective in a mouse model of amyotrophic later...

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Bibliographic Details
Main Authors: Giniatullina Raisa, Goldsteins Gundars, Ahtoniemi Toni, Wojciechowski Sara, Malm Tarja, Kanninen Katja, Jaronen Merja, Savchenko Ekaterina, Pollari Eveliina, Giniatullin Rashid, Koistinaho Jari, Magga Johanna
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Journal of Neuroinflammation
Subjects:
Amyotrophic lateral sclerosis
GCSF
pegfilgrastim
inflammation
monocytes
cytokines
Online Access:http://www.jneuroinflammation.com/content/8/1/74

Internet

http://www.jneuroinflammation.com/content/8/1/74

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