Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice

• Main Authors: Carlos González-Sánchez, Juan-Carlos Fraile, Javier Pérez-Turiel, Ellen Damm, Jochen G. Schneider, Heiko Zimmermann, Daniel Schmitt, Frank R. Ihmig
• Format: Article
• Language: English
• Published: MDPI AG 2016-07-01
• Series: Sensors
• Subjects: non-invasive sensor; capacitive sensors; physiological signals in mice; stress in mice
• Online Access: http://www.mdpi.com/1424-8220/16/7/1052

Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown.