CD8+ T cells in Leishmania infections: friends or foes?

Host protection against several intracellular pathogens requires the induction of CD8+ T cell responses. CD8+ T cells are potent effector cells that can produce high amounts of pro-inflammatory cytokines and kill infected target cells efficiently. However, a protective role for CD8+ T cells during L...

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Bibliographic Details
Main Authors: Simona eStager, Sima eRafati
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00005/full