Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity
When a T cell infiltrates a tumor, it is subjected to a variety of immunosuppressive and regulatory signals in the microenvironment. However, it is becoming increasingly clear that due to the proliferative and energetically-deregulated nature of tumor cells, T cells also operate at a metabolic disad...
Main Authors: | Nicole E. Scharping, Greg M. Delgoffe |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-12-01
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Series: | Vaccines |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-393X/4/4/46 |
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