Astragalus Polysaccharide Attenuated Iron Overload-Induced Dysfunction of Mesenchymal Stem Cells via Suppressing Mitochondrial ROS

Astragalus Polysaccharide Attenuated Iron Overload-Induced Dysfunction of Mesenchymal Stem Cells via Suppressing Mitochondrial ROS

Background/Aims: Bone marrow-derived mesenchymal stem cells (BMSCs) have the ability to differentiate into multilineage cells such as osteoblasts, chondrocytes, and cardiomyocytes. Dysfunction of BMSCs in response to pathological stimuli participates in the development of diseases such as osteoporos...

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Bibliographic Details
Main Authors: Fan Yang, Gege Yan, Yuan Li, Zhenbo Han, Lai Zhang, Simon Chen, Chao Feng, Qi Huang, Fengzhi Ding, Ying Yu, Chongwei Bi, Benzhi Cai, Lei Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Astragalus polysaccharide
Iron overload
Senescence
ROS
Proliferation
Online Access:http://www.karger.com/Article/FullText/447841

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