Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect

Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect

Objective Based on rapid advancement of genetic modification techniques, genomic editing is expected to become the most efficient tool for improvement of economic traits in livestock as well as poultry. In this study, we examined and verified the nickase of mutated CRISPR-associated protein 9 (Cas9)...

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Bibliographic Details
Main Authors: Jeong Hyo Lee, Si Won Kim, Tae Sub Park
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2017-05-01
Series:Asian-Australasian Journal of Animal Sciences
Subjects:
Genome Editing
Cas9
Nickase
Myostatin
Knockout
Poultry
Online Access:http://www.ajas.info/upload/pdf/ajas-30-5-743.pdf

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