History of Newborn Screening for Cystic Fibrosis—The Early Years

History of Newborn Screening for Cystic Fibrosis—The Early Years

This review summarises the trajectory of neonatal screening strategies for the detection of cystic fibrosis (CF) using the measurement of Immunoreactive Trypsin (IRT) in dried blood spots (DBS) from 1979 until the beginning of the 21st century when newborn screening (NBS) programmes started to sprea...

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Bibliographic Details
Main Authors: Georges Travert, Mary Heeley, Anthony Heeley
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Neonatal Screening
Subjects:
newborn screening
immunoreactive trypsin(ogen)
dried blood spot
radioimmunoassay
dna
Online Access:https://www.mdpi.com/2409-515X/6/1/8
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spelling doaj-18e2cc71c73a48d9bf38b1080d697b152020-11-25T01:42:39ZengMDPI AGInternational Journal of Neonatal Screening2409-515X2020-01-0161810.3390/ijns6010008ijns6010008History of Newborn Screening for Cystic Fibrosis—The Early YearsGeorges Travert0Mary Heeley1Anthony Heeley2University of Caen Normandy (UNICAEN), 14032 Caen, FranceEast Anglian Biochemical Genetic Unit, Peterborough, UKEast Anglian Biochemical Genetic Unit, Peterborough, UKThis review summarises the trajectory of neonatal screening strategies for the detection of cystic fibrosis (CF) using the measurement of Immunoreactive Trypsin (IRT) in dried blood spots (DBS) from 1979 until the beginning of the 21st century when newborn screening (NBS) programmes started to spread throughout many countries, using IRT measurement combined with a CF genotype analysis of DBS.https://www.mdpi.com/2409-515X/6/1/8newborn screeningimmunoreactive trypsin(ogen)dried blood spotradioimmunoassaydna
collection DOAJ
language English
format Article
sources DOAJ
author Georges Travert
Mary Heeley
Anthony Heeley
spellingShingle Georges Travert
Mary Heeley
Anthony Heeley
History of Newborn Screening for Cystic Fibrosis—The Early Years
International Journal of Neonatal Screening
newborn screening
immunoreactive trypsin(ogen)
dried blood spot
radioimmunoassay
dna
author_facet Georges Travert
Mary Heeley
Anthony Heeley
author_sort Georges Travert
title History of Newborn Screening for Cystic Fibrosis—The Early Years
title_short History of Newborn Screening for Cystic Fibrosis—The Early Years
title_full History of Newborn Screening for Cystic Fibrosis—The Early Years
title_fullStr History of Newborn Screening for Cystic Fibrosis—The Early Years
title_full_unstemmed History of Newborn Screening for Cystic Fibrosis—The Early Years
title_sort history of newborn screening for cystic fibrosis—the early years
publisher MDPI AG
series International Journal of Neonatal Screening
issn 2409-515X
publishDate 2020-01-01
description This review summarises the trajectory of neonatal screening strategies for the detection of cystic fibrosis (CF) using the measurement of Immunoreactive Trypsin (IRT) in dried blood spots (DBS) from 1979 until the beginning of the 21st century when newborn screening (NBS) programmes started to spread throughout many countries, using IRT measurement combined with a CF genotype analysis of DBS.
topic newborn screening
immunoreactive trypsin(ogen)
dried blood spot
radioimmunoassay
dna
url https://www.mdpi.com/2409-515X/6/1/8
work_keys_str_mv AT georgestravert historyofnewbornscreeningforcysticfibrosistheearlyyears
AT maryheeley historyofnewbornscreeningforcysticfibrosistheearlyyears
AT anthonyheeley historyofnewbornscreeningforcysticfibrosistheearlyyears
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