Serological diagnosis of hepatocellular carcinoma: challenges and opportunities

Serological diagnosis of hepatocellular carcinoma: challenges and opportunities

Serological markers have the features of noninvasiveness and simple operation and thus have become a research hotspot in the diagnosis of hepatocellular carcinoma. This article briefly introduces the role of the conventional serological marker alpha-fetoprotein (AFP) in assisting the diagnosis and p...

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Main Author: LU Fengmin
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2017-07-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=8310
id doaj-18de9dbd376c4a2885a18840af9365d6
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spelling doaj-18de9dbd376c4a2885a18840af9365d62020-11-24T23:36:48ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562017-07-0133712621265doi:10.3969/j.issn.1001-5256.2017.07.011Serological diagnosis of hepatocellular carcinoma: challenges and opportunitiesLU Fengmin0Department of Pathogenic Biology, School of Basic Medical Sciences, Peking University, Beijing 100191, ChinaSerological markers have the features of noninvasiveness and simple operation and thus have become a research hotspot in the diagnosis of hepatocellular carcinoma. This article briefly introduces the role of the conventional serological marker alpha-fetoprotein (AFP) in assisting the diagnosis and predicting the prognosis of HBV-related liver cancer, as well as the clinical value of new markers such as alpha-fetoprotein-L3 and abnormal prothrombin/des-γ-carboxy prothrombin. Based on literature review, the possibility of serum Golgi protein 73 used for laboratory auxiliary diagnosis of hepatocellular carcinoma has been denied. The results of the author′s experiment suggest that serum GP73 measurement can be used as a laboratory diagnostic index for progressive liver fibrosis and liver cirrhosis. http://www.lcgdbzz.org/qk_content.asp?id=8310
collection DOAJ
language zho
format Article
sources DOAJ
author LU Fengmin
spellingShingle LU Fengmin
Serological diagnosis of hepatocellular carcinoma: challenges and opportunities
Linchuang Gandanbing Zazhi
author_facet LU Fengmin
author_sort LU Fengmin
title Serological diagnosis of hepatocellular carcinoma: challenges and opportunities
title_short Serological diagnosis of hepatocellular carcinoma: challenges and opportunities
title_full Serological diagnosis of hepatocellular carcinoma: challenges and opportunities
title_fullStr Serological diagnosis of hepatocellular carcinoma: challenges and opportunities
title_full_unstemmed Serological diagnosis of hepatocellular carcinoma: challenges and opportunities
title_sort serological diagnosis of hepatocellular carcinoma: challenges and opportunities
publisher Editorial Department of Journal of Clinical Hepatology
series Linchuang Gandanbing Zazhi
issn 1001-5256
1001-5256
publishDate 2017-07-01
description Serological markers have the features of noninvasiveness and simple operation and thus have become a research hotspot in the diagnosis of hepatocellular carcinoma. This article briefly introduces the role of the conventional serological marker alpha-fetoprotein (AFP) in assisting the diagnosis and predicting the prognosis of HBV-related liver cancer, as well as the clinical value of new markers such as alpha-fetoprotein-L3 and abnormal prothrombin/des-γ-carboxy prothrombin. Based on literature review, the possibility of serum Golgi protein 73 used for laboratory auxiliary diagnosis of hepatocellular carcinoma has been denied. The results of the author′s experiment suggest that serum GP73 measurement can be used as a laboratory diagnostic index for progressive liver fibrosis and liver cirrhosis.
url http://www.lcgdbzz.org/qk_content.asp?id=8310
work_keys_str_mv AT lufengmin serologicaldiagnosisofhepatocellularcarcinomachallengesandopportunities
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