Pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 – An emerging problem of PICU: A case series

• Main Authors: Bal Mukund, Manoj Sharma, Ankit Mehta, Ashutosh Kumar, Vivek Bhat
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2020-01-01
• Series: Journal of Pediatric Critical Care
• Subjects: coronavirus disease 2019; inflammatory markers; intravenous immunoglobulin; kawasaki disease; pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2; world health organization
• Online Access: http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2020;volume=7;issue=5;spage=271;epage=275;aulast=Mukund
• ISSN: 2349-6592; 2455-7099

Among rising number of coronavirus disease 2019 cases in children, there has been a rapid rise in cases of pediatric multisystem inflammatory syndrome associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS) with clinical features either simulating Kawasaki disease or toxic shock syndrome. We report three children who initially presented with fever, multisystem involvement, and features of hyperinflammation satisfying the World Health Organization criteria for PIMS-TS clinically and on laboratory investigations. All patients were treated with immune modulation by intravenous immunoglobulin and/or methylprednisolone and recovered to discharge.