CellWalker integrates single-cell and bulk data to resolve regulatory elements across cell types in complex tissues
Abstract Single-cell and bulk genomics assays have complementary strengths and weaknesses, and alone neither strategy can fully capture regulatory elements across the diversity of cells in complex tissues. We present CellWalker, a method that integrates single-cell open chromatin (scATAC-seq) data w...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-02-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-021-02279-1 |