Necrobiosis lipoidica in diabetic patients: pathogenetic and clinical features

Necrobiosis lipoidica in diabetic patients: pathogenetic and clinical features

Necrobiosis lipoidica (NL) is a chronic skin disease (dermatosis) associated with various metabolic disorders including carbohydrate metabolism.In the last years, NL has been increasingly frequently diagnosed by practitioners probably due to the rise in type 2 diabetes mellitus morbidity in thegener...

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Bibliographic Details
Main Authors: Daria Alexandrovna Semenova, Alla Yur'evna Tokmakova
Format: Article
Language:English
Published: Endocrinology Research Centre 2011-12-01
Series:Сахарный диабет
Subjects:
diabetes mellitus
necrobiosis lipoidica
pathogenesis
histology
toll-receptors
Online Access:https://dia-endojournals.ru/dia/article/viewFile/5817/3576
Description
Summary:Necrobiosis lipoidica (NL) is a chronic skin disease (dermatosis) associated with various metabolic disorders including carbohydrate metabolism.In the last years, NL has been increasingly frequently diagnosed by practitioners probably due to the rise in type 2 diabetes mellitus morbidity in thegeneral population. Moreover, association of NL with autoimmune thyroid diseases, Crohns disease, ulcerative colitis, sarcoidosis, and vitiligo hasbeen documented. Such cases may be attributed to phenotypic and functional defects of cellular immunity.
ISSN:2072-0351
2072-0378

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