Sites of high local frustration in DNA origami
Self-assembly of DNA origami is a complex folding problem without a unified view of the energetic factors involved. Here the authors analyse identical structures that differ by nucleotide sequence and identify how mechanical stress at nucleation sites shapes the energy landscape.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2019-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-09002-6 |
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Article |
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doaj-18c3fb80b55445e2b7a1c1e064f84fa52021-05-11T12:31:03ZengNature Publishing GroupNature Communications2041-17232019-03-0110111210.1038/s41467-019-09002-6Sites of high local frustration in DNA origamiRichard Kosinski0Ann Mukhortava1Wolfgang Pfeifer2Andrea Candelli3Philipp Rauch4Barbara Saccà5ZMB, University of Duisburg-EssenLUMICKS, De Boelelaan 1085ZMB, University of Duisburg-EssenLUMICKS, De Boelelaan 1085LUMICKS, De Boelelaan 1085ZMB, University of Duisburg-EssenSelf-assembly of DNA origami is a complex folding problem without a unified view of the energetic factors involved. Here the authors analyse identical structures that differ by nucleotide sequence and identify how mechanical stress at nucleation sites shapes the energy landscape.https://doi.org/10.1038/s41467-019-09002-6 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Richard Kosinski Ann Mukhortava Wolfgang Pfeifer Andrea Candelli Philipp Rauch Barbara Saccà |
| spellingShingle |
Richard Kosinski Ann Mukhortava Wolfgang Pfeifer Andrea Candelli Philipp Rauch Barbara Saccà Sites of high local frustration in DNA origami Nature Communications |
| author_facet |
Richard Kosinski Ann Mukhortava Wolfgang Pfeifer Andrea Candelli Philipp Rauch Barbara Saccà |
| author_sort |
Richard Kosinski |
| title |
Sites of high local frustration in DNA origami |
| title_short |
Sites of high local frustration in DNA origami |
| title_full |
Sites of high local frustration in DNA origami |
| title_fullStr |
Sites of high local frustration in DNA origami |
| title_full_unstemmed |
Sites of high local frustration in DNA origami |
| title_sort |
sites of high local frustration in dna origami |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2019-03-01 |
| description |
Self-assembly of DNA origami is a complex folding problem without a unified view of the energetic factors involved. Here the authors analyse identical structures that differ by nucleotide sequence and identify how mechanical stress at nucleation sites shapes the energy landscape. |
| url |
https://doi.org/10.1038/s41467-019-09002-6 |
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