Single-crosslink microscopy in a biopolymer network dissects local elasticity from molecular fluctuations

The intrinsic inhomogeneity of polymer networks is masked by the usual ensemble-averaged measurements. Here the authors construct direct maps of crosslinks in an actin network by selective labeling the crosslinks with fluorescent markers and characterize the local elasticity and cross-correlation be...

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Bibliographic Details
Main Authors: Lingxiang Jiang, Qingqiao Xie, Boyce Tsang, Steve Granick
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11313-7
Description
Summary:The intrinsic inhomogeneity of polymer networks is masked by the usual ensemble-averaged measurements. Here the authors construct direct maps of crosslinks in an actin network by selective labeling the crosslinks with fluorescent markers and characterize the local elasticity and cross-correlation between crosslinks.
ISSN:2041-1723