IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis

IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis

The IL-1 family member cytokine IL-36γ is recognised as key mediator in the immunopathology of psoriasis, hallmarks of which involve the activation of both resident and infiltrating inflammatory myeloid cells and aberrant angiogenesis. This research demonstrates a role for IL-36γ in both myeloid act...

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Bibliographic Details
Main Authors: Charlie Bridgewood, Gareth W. Fearnley, Anna Berekmeri, Philip Laws, Tom Macleod, Sreenivasan Ponnambalam, Martin Stacey, Anne Graham, Miriam Wittmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
psoriasis
IL-36γ
IL-23
macrophages
monocytes
angiogenesis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00200/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00200/full

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