Electrophysiological Characterization of Nicotine-Induced Excitation of Dopaminergic Neurons in the Rat Substantia Nigra

ABSTRACT: The electrophysiological characteristics of nicotine-induced excitation of dopaminergic neurons in the rat substantia nigra was investigated using the whole-cell patch clamp technique under the voltage-clamp mode. Nicotine (0.01 – 100 μM) induced inward currents corresponding to nicotine-i...

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Bibliographic Details
Main Authors: Hiroaki Matsubayashi, Taku Amano, Takahiro Seki, Masashi Sasa, Norio Sakai
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325903