Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells

OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm. Here the authors use single cell pH imaging to define the role of OmpR-regulated genes in the acidification response to osmotic and acid stress of Sa...

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Bibliographic Details
Main Authors: Smarajit Chakraborty, Ricksen S. Winardhi, Leslie K. Morgan, Jie Yan, Linda J. Kenney
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02030-0
Description
Summary:OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm. Here the authors use single cell pH imaging to define the role of OmpR-regulated genes in the acidification response to osmotic and acid stress of Salmonella and E. coli.
ISSN:2041-1723