Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans
Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE-/- mice, we induced unstable plaque with using...
Main Authors: | Dolf Segers, Jonathan A. Lipton, Pieter J. M. Leenen, Caroline Cheng, Dennie Tempel, Gerard Pasterkamp, Frans L. Moll, Rini de Crom, Rob Krams |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
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Series: | International Journal of Inflammation |
Online Access: | http://dx.doi.org/10.4061/2011/936109 |
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