A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies

The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex mechanically couples cytoskeletal and nuclear components across the nuclear envelope to fulfil a myriad of cellular functions, including nuclear shape and positioning, hearing, and meiotic chromosome movements. The canonical model is that...

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Bibliographic Details
Main Authors: Manickam Gurusaran, Owen Richard Davies
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
LINC complex
nuclear envelope
SUN1
Nesprin-1
Nesprin-4
KASH5
Online Access:https://elifesciences.org/articles/60175

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