Implementation of a CRISPR-Based System for Gene Regulation in Candida albicans
CRISPR technology is a new and efficient way to edit genomes, but it is also an appealing way to regulate gene expression. We have implemented CRISPR as a gene expression platform in Candida albicans using fusions between a Cas9 inactive enzyme and specific repressors or activators and demonstrated...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2019-02-01
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| Series: | mSphere |
| Subjects: | |
| Online Access: | https://doi.org/10.1128/mSphere.00001-19 |