Immunolocalization and Distribution of Rubella Antigen in Fatal Congenital Rubella Syndrome

Immunolocalization and Distribution of Rubella Antigen in Fatal Congenital Rubella Syndrome

Background: An estimated 100,000 cases of congenital rubella syndrome (CRS) occur worldwide each year. The reported mortality rate for infants with CRS is up to 33%. The cellular mechanisms responsible for the multiple congenital defects in CRS are presently unknown. Here we identify cell types posi...

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Bibliographic Details
Main Authors: Mihaela Lazar, Ludmila Perelygina, Roosecelis Martines, Patricia Greer, Christopher D. Paddock, Gheorghe Peltecu, Emilia Lupulescu, Joseph Icenogle, Sherif R. Zaki
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:EBioMedicine
Subjects:
Congenital rubella syndrome (CRS)
CRS pathology
Immunohistochemistry
Fatal cases
Autopsy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415302334

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