Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer

Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer

Background: The observation of tumor-derived cell-free DNA (ctDNA) in plasma brought new expectations to monitor treatment response in cancer patients.Case presentation: In an exploratory case of a 57-year-old man diagnosed with metastatic sigmoid adenocarcinoma, we used a hotspot panel of cancer-as...

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Bibliographic Details
Main Authors: Bruna D. de Figueiredo Barros, Bruna E. C. Kupper, Samuel Aguiar Junior, Celso A. L. de Mello, Maria D. Begnami, Rubens Chojniak, Sandro J. de Souza, Giovana T. Torrezan, Dirce M. Carraro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Oncology
Subjects:
liquid biopsy
ctDNA
colorectal cancer
NGS
gene panel
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00306/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00306/full

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