RNAi-mediated knockdown of MTNR1B without disrupting the effects of melatonin on apoptosis and cell cycle in bovine granulose cells

RNAi-mediated knockdown of MTNR1B without disrupting the effects of melatonin on apoptosis and cell cycle in bovine granulose cells

Melatonin is well known as a powerful free radical scavenger and exhibits the ability to prevent cell apoptosis. In the present study, we investigated the role of melatonin and its receptor MTNR1B in regulating the function of bovine granulosa cells (GCs) and hypothesized the involvement of MTNR1B i...

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Bibliographic Details
Main Authors: Wenju Liu, Shujuan Wang, Jinxing Zhou, Xunsheng Pang, Like Wang
Format: Article
Language:English
Published: PeerJ Inc. 2018-04-01
Series:PeerJ
Subjects:
Apoptosis
Granulosa cell
Melatonin
MTNR1B
RNA interference
Online Access:https://peerj.com/articles/4463.pdf

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