Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

<p>Abstract</p> <p>Background</p> <p>Kisspeptins and their G-protein coupled receptor, GPR54 are required for GnRH release and have been associated with anti-metastatic tumour cell behaviour in model systems. The latter might suggest that their overexpression would be a...

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Main Authors: Mehl Erika, Kenney Challayne, Santos Jennifer L, McKinney Steven, Köbel Martin, Kalloger Steve, Klausen Christian, Prentice Leah M, Gilks C Blake, Leung Peter, Swenerton Ken, Huntsman David G, Aparicio Samuel AJ
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/5/33

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